Centuries ago, merchants and shippers would place a lit candle inside barrels used to store biscuits before closing the lid. The idea was that the candle flame would deplete the oxygen inside the barrel to help keep the biscuits from spoiling. These days, the candle flame has been replaced by processes called Modified Atmosphere Packaging (MAP), which can be either active or passive. By altering the atmosphere inside food product packages, or by using specialized packaging films, today’s food processors can preserve freshness and taste; extend shelf-life; prevent oxidation, which can lead to food spoilage; and protect against crushing the food contents inside the packaging, all without the use of chemical additives, stabilizers, or even candles.

Why Use Modified Atmosphere Packaging?
​Consumers want food that not only looks, tastes, and smells good, but is also convenient and lasts longer than a few days after purchase. In order to satisfy consumers, food packagers need to eliminate or, at least, control factors that contribute to food spoilage, including improper levels of moisture, temperature, or light; excessive oxygen (i.e., oxidation); and the growth of microorganisms (such as mold or pathogens that can lead to food-borne illnesses).

Spoiled food means lost revenues and lower profits for producers and intermediaries, higher food prices passed on to the consumer, and an environmental burden, as food waste reportedly contributes to some 8% of global greenhouse gas emissions.

How Does MAP Work?
Active modified atmosphere packaging works by changing the atmosphere inside food packaging, typically by the introduction of gases. For instance, carbon dioxide is often used to remove oxygen from inside the packaging of breads and other baked goods, in order to keep the products from going stale, prevent mold growth, and to extend shelf-life.
Packaged foods with high-fat content, such as certain cheeses or fish high in fatty acids, require a high concentration of carbon dioxide to prevent mold growth and to prevent the cheese or fish from tasting  rancid. However, excessive levels of  carbon dioxide can make certain foods taste sour. To prevent that from occurring, food packagers may elect to use nitrogen, or a mixture of gases, instead of carbon dioxide alone.

Conversely, while certain meat, fish, and poultry require that all or almost all oxygen be removed from inside packaging and replaced with carbon dioxide and/or nitrogen to prevent microbial growth and spoilage, oxygen is actually added to some packaged meats, low-fat fish, and shellfish to prevent fading or loss of color, as well as to inhibit the growth of certain types of bacteria.

Adding nitrogen gas to packaging not only helps salty snack foods stay crispy and fresh by displacing the oxygen inside food packaging, but it also helps protect the contents from getting crushed or broken during transport of the products from manufacturing facilities to stores and, ultimately, to consumers’ pantries.

Fresh fruits and vegetables are often packaged by using a passive form of MAP which includes specialized, permeable packaging films. The permeable film allows the fresh produce to continue to respire (that is, breathe) after being harvested, but at a much slower rate than if it were still on the plant. Low oxygen levels, combined with carbon dioxide or nitrogen, help to preserve the freshness, taste, and appearance of fresh fruits and vegetables.

Proper Monitoring Can Preserve Food Products and Protect Packaging Personnel
Balancing the correct mixture of oxygen, carbon dioxide and nitrogen is vital when it comes to food packaging. Too much or too little of a required gas can lead to foods that have unappetizing taste, smell, or appearance and, in baked goods, can promote mold growth, and staleness.

Moreover, food packagers and others working around carbon dioxide and nitrogen need to be aware of the potential safety risks associated with these odorless and colorless oxygen-depleting gases. According to the Occupational Safety and Health Administration (OSHA), an environment in which oxygen levels fall below 19.5 percent is considered an oxygen-deficient atmosphere and should be treated as immediately dangerous to health or life. When there is not enough oxygen in the air, persons working in the affected area may become disoriented, lose consciousness, or even suffocate due to the lack of sufficient oxygen.

Because carbon dioxide and nitrogen are devoid of odor and color, individuals working around these gases might well, in the absence of appropriate monitoring equipment, be unaware that a safety risk situation has developed.

PureAire Monitors

PureAire Monitoring Systems’ Dual Oxygen/Carbon Dioxide Monitor offers thorough air monitoring, with no time-consuming maintenance or calibration required. A screen displays current oxygen and carbon dioxide levels for at-a-glance reading by food packaging employees, who derive peace of mind from the Monitor’s presence and reliable performance.

In the event of a carbon dioxide or nitrogen gas leak, and a decrease in oxygen to an unsafe level, PureAire’s Monitor will set off an alarm, complete with horns and flashing lights, alerting personnel to evacuate the area.
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PureAire’s Dual Oxygen/Carbon Dioxide Monitor is well-suited for facilities where gases such as carbon dioxide and nitrogen are used. Our Dual O2/CO2 monitor includes both a non-depleting, zirconium oxide sensor cell, to monitor oxygen levels, and a non-dispersive infrared (NDIR) sensor cell, to monitor carbon dioxide levels. PureAire’s O2/CO2 monitors can last, trouble-free, for over 10 years under normal operating conditions.

In December 2020,  two employees working at a Vernon, California food processing plant lost consciousness and died following an apparent liquid nitrogen leak. On January 28, 2021, there were several fatalities, and many other employees became sick, after being exposed to nitrogen gas when a liquid nitrogen line ruptured at a food processing plant in Gainesville, Georgia.According to the Occupational Safety and Health Administration (OSHA), a total of fourteen workers died from asphyxiation linked to nitrogen gas in twelve separate workplace accidents recorded between 2012 and 2020, and 2021 is already off to a sad start.  Tragically, these accidents illustrate the dangers of working with liquid nitrogen.
Importance of Liquid Nitrogen in Food Processing
Liquid nitrogen (LN2) is used in food processing in a number of applications, including grinding, mixing, coating, freezing, and packaging foods. Food processors may use liquid nitrogen in the production of a variety of foods, such as meat, poultry, seafood, fruits, vegetables, baked goods, and prepackaged meals. The very low temperature of LN2 is used to flash-freeze foods to help prevent microbial growth that can lead to food spoilage, and to maintain the foods’ original freshness, flavor, and textures.
Oxygen Monitors Can Reduce the Risk of Liquid Nitrogen Accidents
While the use of liquid nitrogen is important in food processing, it is not without risk. When liquid nitrogen is exposed to the air (which happens when leaks occur), it will evaporate, changing from a liquid to an oxygen-depleting gas. Oxygen deprivation can put employees in real danger if there are leaks from pressurized LN2 freezer lines, exhaust systems, or on-site storage containers. In the event of a liquid nitrogen leak, food processing workers could become disoriented, lose consciousness, or even suffocate from breathing oxygen-deficient air. Since LN2 is both odorless and colorless, workers would, in the absence of appropriate monitoring, have no way of knowing that there has been a liquid nitrogen leak.
However, by utilizing a top-quality oxygen deficiency monitor, food plant personnel can safely track oxygen levels and detect leaks before workers’ health is jeopardized.Best practice calls for oxygen deficiency monitors to be installed anywhere there is a risk of liquid nitrogen gas leaks. The monitor should be placed wherever liquid nitrogen is stored, and in all areas where liquid nitrogen is used. The monitoring equipment should include visual and audible alarms that would be activated in the event of liquid nitrogen leaks and a decrease in oxygen levels.
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PureAire Monitors

​PureAire Monitoring Systems’ line of oxygen deficiency monitors, including a water-resistant unit for facilities requiring daily wash-downs, offers thorough air monitoring, with no time-consuming maintenance or calibration required. In the event of a liquid nitrogen leak, and a decrease in oxygen to an unsafe level, PureAire’s oxygen deficiency monitor will set off an alarm, complete with horns and flashing lights, alerting personnel to evacuate the area. PureAire oxygen deficiency monitors are ideally suited for use in food processing facilities because the monitors can withstand temperatures as low as -40 Celsius. Each PureAire O2 monitor has an easy to read screen, which displays current oxygen levels, for at-a-glance reading by food processing employees, who derive peace of mind from the monitor’s presence and reliable performance.

Overview
In modern times, vaccines have been widely used to keep people healthy by protecting them from serious illnesses and diseases. Worldwide, vaccines annually prevent millions of deaths, and their utilization is responsible, in many parts of the globe, for the nearly total eradication of numerous diseases, including polio, measles, and smallpox.

According to the U.S. Centers for Disease Control (the "CDC"), a vaccine for a specific disease stimulates an individual's immune system, causing it to produce antibodies to counteract the antigens associated with the disease in question, just as one's immune system would do if one were actually exposed to the disease. The concept is that, after getting vaccinated, the inoculated patient develops immunity to the disease without first having to contract it. Unlike medicines, which are used to treat or cure diseases, vaccines are intended to prevent them.

Handling and Storage of Vaccines
Developing a vaccine can take years before it is deemed safe for human use and, thereafter manufactured and made available for widespread distribution and inoculation. Throughout the manufacturing and  distribution process, and up to the time of administration, a vaccine must be kept in strict climate-controlled environments, collectively referred to as the "cold chain." The CDC describes a cold chain as a temperature-controlled supply chain that includes all vaccine-related equipment and procedures. The vaccine cold chain begins with a cold storage unit at the vaccine manufacturing plant, extends to the transport and delivery of the vaccine (including proper storage at the provider facility), and ends with the administration of the vaccine to the patient. A breakdown in protocols anywhere along the cold chain could reduce the effectiveness of, or even destroy, a vaccine.

According to FedEx, while most  vaccines have traditionally been transported in a cold temperature range of 2 degrees Celsius to 8 degrees Celsius, certain vaccine manufacturers and pharmaceutical firms require a much lower temperature range within the cold chain associated with specific vaccine products.

Dry ice, which is the common name for solid (i.e., frozen) carbon dioxide, is often used in cold chains to maintain the very cold temperatures required to keep certain vaccines viable. At a temperature of approximately -78.5 degrees Celsius (equating to  -109.3 degrees Fahrenheit), dry ice is significantly colder than frozen water (that is, conventional ice), making it ideal for transport and storage of those vaccines requiring an extremely cold temperature environment.

Safely Tracking Carbon Dioxide Levels When Working with Dry Ice
Safety precautions are critical when shippers use dry ice in the transportation and storage of vaccines. Unlike conventional ice, dry ice does not melt into a liquid. Instead,  dry ice "sublimates" (changes from a solid to a gas state), turning into carbon dioxide gas. In small, poorly ventilated spaces, such as storage rooms and closets, cargo vans, trucks, and airplanes, carbon dioxide can build up, creating a potentially serious health risk.

Carbon dioxide is an oxygen-depleting gas that is both odorless and colorless. As such, absent appropriate monitoring, workers involved with the transportation and/or storage of products frozen with dry ice likely would be unable to detect if dry ice were to begin to sublimate, with carbon dioxide gas levels possibly rising to unsafe levels. When there is not enough oxygen in the air, persons working in the affected area may become disoriented, lose consciousness, or even suffocate due to the lack of oxygen

Fortunately, by utilizing a top-quality oxygen monitor, also known as an oxygen deficiency monitor, vaccine transportation storage personnel can track oxygen levels and detect (and react to) dangerous carbon dioxide levels before employee health is jeopardized.
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PureAire Dual Oxygen/Carbon Dioxide Monitor

PureAire Monitoring Systems' Dual Oxygen/Carbon Dioxide Monitor offers thorough air monitoring, with no time-consuming maintenance or calibration required.  A screen displays current oxygen and carbon dioxide levels, for at-a-glance reading by employees, who derive peace of mind from the Monitor's presence and reliable performance.
In the event that dry ice begins to sublimate, causing carbon dioxide levels to rise, and oxygen to decrease to unsafe levels, PureAire's Monitor will  set off an alarm, complete with horns and flashing lights, alerting personnel to evacuate the area.
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Our Dual Oxygen/Carbon Dioxide Monitor is well-suited for industries where dry ice is used, such as in the handling, transportation, and storage of life-saving vaccines. The Monitor includes both a non-depleting, zirconium oxide sensor cell, to monitor oxygen levels, and a non-dispersive infrared (NDIR) sensor cell, to monitor carbon dioxide levels. Known for their dependability, PureAire's O2/CO2 Monitors can last, trouble free, for over 10 years under normal operating conditions.

MRI
Magnetic resonance imaging (MRI) is a diagnostic procedure that uses a combination of a very large magnet, radio waves, and a computer to produce detailed, cross-sectional, and three-dimensional images of organs and structures within the body.
An MRI scan is a valuable diagnostic tool that can show injuries or other anomalies that cannot be seen in a CT scan or X-ray.  For instance, soft tissue injuries, such as, strains, sprains, contusions, tendonitis, and bursitis can all be observed via MRI.
Moreover, according to the Mayo Clinic, MRI can also be used to diagnose a variety of brain-related and nervous system disorders, including strokes, aneurysms, multiple sclerosis, eye and inner ear problems, and spinal cord injuries. MRI is widely used in research on brain structures and functions.
How MRI Works
MRI scanning machines vary in size, shape, and degree of openness but the typical MRI machine resembles a tube (encompassing a very large magnet) with a table in the middle, which enables the patient to lie down and slide into the magnetic field created inside the machine. The magnet itself is comprised of multiple coils of connective wire through which a current is passed to generate a magnetic field. To achieve the high field strengths required for most clinical needs, the magnet is cooled with liquid helium to -452 degrees Fahrenheit (-270 Celsius). The super cold temperature applied to the magnet provides for “superconductivity”, meaning that current can pass through the magnet’s coils without electrical resistance, producing the type of strong magnetic field necessary to produce detailed images.
To ensure accurate imaging, and to preserve the integrity of the MRI scanning machine, the liquid helium must be kept extremely cold when the scanner is in operation. If the temperature of the liquid helium were to rise above the very cold levels required for superconductivity, the helium might vaporize and, with the dissipation of the liquid helium’s super-cooling properties,  the machine’s magnet could overheat, potentially causing irreparable damage to the MRI machine.
Oxygen Monitors Can Detect Helium Leaks
Helium is an odorless, colorless, oxygen-depleting gas that can rapidly displace oxygen in the air to levels below what is needed for humans to breathe. Excess exposure to helium can cause dizziness, nausea, and loss of consciousness, and could even result in death within seconds of exposure. Because liquid helium is devoid of color and odor, MRI personnel would, absent appropriate oxygen monitoring, likely be unaware that a potentially dangerous helium leak has occurred. As such, the National Institutes of Health’s Design Requirements Manual recommends that oxygen monitors be installed in MRI treatment areas.
Proper oxygen monitoring equipment should be placed in MRI rooms, as well as in storage rooms, and in any other site where helium gas may accumulate. The monitoring equipment should include visual and audible alarms that would be activated in the event of helium leaks and a decrease in oxygen levels.

PureAire Oxygen Deficiency Monitors
PureAire Monitoring Systems’ Sample Draw Oxygen Deficiency Monitor continuously tracks levels of oxygen and will detect helium leaks before MRI machines are damaged and the health of employees and patients is put at risk.​

The Monitor’s built-in pump samples oxygen from up to 100 feet away, making it ideal for use in MRI facilities, because the metal components within the Monitor are outside the imaging area and, therefore, will not interfere with the magnets that are the heart of MRI scanning machines.
PureAire’s durable, non-depleting, zirconium oxide sensor can last 10+ years in a normal environment, without needing to be replaced.
In the event of a helium gas leak, and a decrease in oxygen to an unsafe, OSHA action level, the Sample Draw Oxygen Monitor will set off an alarm, complete with horns and flashing lights, alerting staff and patients to evacuate the area. Additionally, the same alarm will alert personnel to turn off the MRI scanner in order to prevent the magnet overheating that could result in possible damage to the machine.
PureAire’s Sample Draw Oxygen Deficiency Monitor has an easy to read screen, which displays current oxygen levels, for at-a-glance observation by MRI employees, who derive peace of mind from the Monitor’s presence and reliability.

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In 1996, California passed Proposition 215, making it the first of many states to ultimately legalize medical cannabis; as of January 2020, an additional 32 states and the District of Columbia have also made medical cannabis legal. Additionally, recreational use of cannabis is now legal in 11 states and is decriminalized in many others. Cannabis legalization and decriminalization have made cannabidiol (“CBD”, a non-psychoactive compound found in cannabis), and tetrahydrocannabinol(“THC”, the chemical responsible for most of cannabis’ mind-altering effects), available to both recreational users and patients seeking treatment for such health issues as arthritis, anxiety, inflammation, seizure disorders, and nausea.
Since California’s groundbreaking move in 1996, medical and recreational cannabis has become a significant and rapidly growing industry. According to DC-based cannabis researcher, New Frontier Data, legal cannabis sales in the U.S. are expected to reach $30 billion annually by 2025. The industry growth has led to a substantial increase in grow rooms, medical dispensaries and other retail outlets, and extraction facilities.
Extraction
Extraction is a process by which desired chemical compounds are extracted and separated from the cannabis plant. Extraction strips the plant of essential oils, including CBD, THC, and terpenes (aromatic oils that give cannabis plants their distinctive scents). The extracted oils can be utilized in vape pens, edibles, capsules, tinctures, and topical solutions. Based on the end product, various techniques can be used for extracting the oils, including carbon dioxide (CO2) extraction and hydrocarbon solvent extraction (using solvents such as butane or propane).
Carbon Dioxide Extraction
Carbon dioxide, high pressure, and heat can be combined to create a “supercritical fluid” that extracts cannabis components from the plant. The CO2 extraction method generally produces high yields with relatively little waste. Temperatures and pressures can be adjusted to create multiple products including vaporizer oils; dabbing concentrates such as so-called waxes, crumble, shatters, and saps; and distillates (cannabis extracts that have been further purified and processed to separate and isolate the various cannabinoids, which include CBD and THC). Because CO2 evaporates on its own, many in the medical products and food and beverage industries find the CO2 extraction method appealing, since no residual carbon dioxide remains in the final manufactured product.
Hydrocarbon Solvents Extraction
Hydrocarbon extraction typically uses organic solvents such as butane and propane to separate essential oils from the plant material. The use of hydrocarbons for extraction is popular owing, in large part, to the relatively low overhead costs, efficiency (including the wide variety of products that can be created from a single extraction, without the need for further refinement), and high product quality associated with this technique. For instance, the low boiling point of butane, and even lower boiling point of propane, allow extractors to remove the desired compounds without risking evaporation of, or damage to, the delicate and heat-sensitive cannabinoids and terpenes. Moreover, their low boiling points makes it relatively easy to purge any residual butane or propane at the end of the extraction process, leaving behind only a relatively pure product.
Oxygen Monitors Can Protect Extractors and Their Employees
 While CO2 and hydrocarbon solvents are important techniques for extracting essential oils from cannabis plants use of these gases is not without risk, since extraction facility personnel and property are exposed to potential leaks from gas supply lines and storage containers.
Carbon dioxide is an oxygen-depleting gas that is both odorless and colorless. As such, absent appropriate monitoring to detect that a leak has occurred, extraction employees could become dizzy, lose consciousness, and even suffocate from breathing oxygen-deficient air. Hydrocarbons such as butane and propane also deplete oxygen and, they are flammable and explosive as well.
Proper gas detection equipment should be placed where the cannabis extraction process takes place, as well as in CO2 and hydrocarbon storage rooms, and in any other site where CO2, butane, and propane may be expected to accumulate. The gas detection equipment should include the capacity to activate visual and audible alarms, stopping the flow of gas and turning on the ventilation system.
PureAire Monitors
PureAire Monitoring Systems has safety monitors to meet the needs of cannabis extractors, whether they use CO2 or hydrocarbon solvents.
For facilities using carbon dioxide to extract their products, PureAire’s line of dual oxygen/carbon dioxide monitors offer thorough air monitoring, with no time-consuming maintenance or calibration required. The O2/CO2 monitor comes with user-adjustable alarm setpoints for both oxygen and carbon dioxide. The monitor is built with zirconium oxide sensor cells and non-dispersive infrared sensor (NDIR)cells, to ensure longevity.PureAire’s O2/CO2 monitors can last, trouble-free, for over 10 years under normal operating conditions.

Extractors utilizing hydrocarbon solvents, such as butane or propane, rely on PureAire’s LEL, explosion-proof, combustible gas monitors. The monitor is housed in a NEMA 4 enclosure specifically designed to prevent an explosion. The durable, long-life LEL catalytic sensor will last 5+ years without needing to be replaced.
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PureAire monitors feature an easy to read screen, which displays current oxygen levels for at-a-glance observation by employees, who derive peace of mind from the monitor’s presence and reliable performance. In the event of a gas leak, or a drop in oxygen to an unsafe OSHA action level, PureAire’s monitors will set off alarms, complete with horns and flashing lights, alerting personnel to evacuate the area. At the same time, the monitors can be programmed to turn off the flow of gas (CO2, butane, or propane, as appropriate), and turn on the ventilation system.
In short, PureAire’s monitors enable cannabis extractors, in a cost-effective manner, to preserve both the quality of their products and the well-being of their employees.

Frozen foods first became commercially viable in the 1930s, thanks in large part to Clarence Birdseye. He is credited with inventing the double-belt freezer, the forerunner to modern quick-freeze technology, which includes the tunnel freezers used by most major food processors in North America.

Frozen foods offer many benefits to today’s busy consumers, including convenience; minimal processing, with few to no preservatives; a long spoilage-free product shelf life; and, especially when compared with canned foods, superior taste, since the ingredients are quick-frozen at their peak of freshness. Seasonal foods, such as fruits and vegetables, are, once they have been frozen, now available year-round. In the same way, people living in landlocked locations can enjoy fresh-frozen seafood, no matter the distance from the coast. And, through the near magic of quick-frozen partially baked bread products, we can consume bakery-quality goods at home, straight out of the ovens in our own kitchens.

Still, even as Mr. Birdseye’s invention made frozen foods available to mass consumers in the first place nearly a century ago, so, too, have more recent innovations in freezing technology, including new freezer types, such as tunnel freezers using cryogenic gases, greatly improved the quality and, therefore, the market acceptance, of frozen foods. These freezers very quickly “flash freeze” foods at extremely low temperatures, such that the foods maintain essentially all of their original freshness, flavor, and texture.

How Tunnel Freezers Work
Tunnel freezers work by rapidly freezing food using cryogenic gases, such as liquid nitrogen (LN2) or carbon dioxide (CO2). The fresh food items are placed on a conveyor belt, which carries them into the freezer, where an injection system (utilizing either liquid nitrogen or carbon dioxide), together with fans circulating the gas-chilled air, ensure that all food surfaces are quickly and evenly frozen.

Food products frozen in cryogenic tunnel freezers, including all manner of proteins, fruits, vegetables, and parbaked bread and dough items, are ultimately shipped to grocery chains and warehouse superstores; operators of quick service, fast casual, and fine dining restaurants; and school and hospital cafeterias, among other places, and they are enjoyed daily by millions of hungry people.

Monitoring Can Protect Food Processing Employees
While the use of liquid nitrogen and/or carbon dioxide is essential in that part of the quick-frozen food processing industry using tunnel freezer technology, it is not without risk. LN2 and CO2 are both oxygen-depleting gases, and oxygen deprivation could put employees in real danger if there are gas leaks from freezer supply lines or exhaust systems, or from on-site gas storage containers. In the event of a leak, plant personnel could become disoriented, lose consciousness, or even suffocate from breathing oxygen-deficient air. Since liquid nitrogen and carbon dioxide are both colorless and odorless, workers would, in the absence of appropriate monitoring, have no way of knowing that there has in fact been a gas leak.
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PureAire Water-Resistant Dual O2/CO2 Monitors 
PureAire Monitoring Systems’ water-resistant dual oxygen/carbon dioxide monitors offer thorough air monitoring, with no time-consuming maintenance or calibration required. A screen displays current oxygen and carbon dioxide levels for at-a-glance reading by employees, who derive peace of mind from the monitor’s presence and reliable performance.

In the event of a nitrogen or carbon dioxide leak, and a decrease in oxygen to an unsafe level, the monitor will set off an alarm, complete with horns and flashing lights, alerting personnel to evacuate the area.
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PureAire’s dual oxygen/carbon dioxide monitor is housed in an IP67 water resistant enclosure that will keep the electronics dry during wash-downs and will remain accurate at extremely low temperatures.That makes the monitor ideally suited for facilities using liquid nitrogen or carbon dioxide, such as frozen food processing plants with tunnel freezers. Built with zirconium oxide sensor cells and non-dispersive infrared sensor (NDIR)cells to ensure longevity, PureAire’s dual O2/CO2 monitors can last, trouble-free, for over 10 years under normal operating conditions.

Cryotherapy
Cryotherapy (also known as cold therapy) is broadly defined as the use of very cold temperatures for medical or general wellness purposes.  Modern cryotherapy (which comes from the Greek kyro, meaning “cold” and therapeia,  meaning “healing”) can be traced back thousands of years, and some form of it was practiced by the ancient Greeks, Romans, and Egyptians, among other civilizations, which used extreme cold therapy to treat injuries and reduce inflammation.

In 1978, a Japanese rheumatologist, Toshima Yamaguchi, developed what is known as Whole Body Cryotherapy (“WBC”), in which, cryotherapy is applied to the entire body; that is, the whole body, except the head, is exposed to extremely cold temperatures. Dr. Yamaguchi’s research found that rapid temperature decreases on the outer layers of individuals’ skin led to a rapid release of endorphins, which caused those individuals to become less sensitive to pain. To put his findings into practice, Dr. Yamaguchi and his associates built the world’s first cryochamber.

How Whole Body Cryotherapy Works
Whole body cryotherapy involves enclosing the entire body (excepting the head) in a cryochamber, with liquid nitrogen used to quickly chill the chamber to temperatures between -200 and -300 degrees Fahrenheit for a period not longer that 2-4 minutes. The extremely rapid cooling of the body causes blood flow to concentrate towards the body’s core, and away from the extremities, which, in concept, can reduce inflammation relating to soft tissue injuries.  At the same time, the body releases endorphins, which serve to decrease pain and increase feelings of euphoria.

Health Benefits Attributed to Whole Body Cryotherapy
Whole body cryotherapy is used to treat patients suffering from chronic inflammatory conditions, as well as, Olympic and other elite athletes experiencing muscle soreness, and to shorten recovery times from injuries and surgeries.

Cryotherapy is used to treat joint pain and inflammation due to arthritis and fibromyalgia, and for pain management, physical therapy, anti-aging, and weight loss treatments.

Oxygen Monitors Can Protect Cryochamber Workers and Users
In 2015, a cryotherapy facility employee in Las Vegas was found dead after she suffocated in a chamber.  The coroner’s office concluded that the death was caused by accidental asphyxiation, resulting from low oxygen levels, possibly resulting from a leak of the nitrogen gas used to rapidly chill the cryochamber. Nitrogen is an oxygen-depleting gas that is both odorless and colorless. Oxygen deprivation is called a silent killer because there are no indications that one is breathing oxygen deficient air until it is too late. As such, absent appropriate monitoring, workers would be unable to detect a nitrogen leak if one were to occur in a gas cylinder or line. Conversely, by utilizing a top-quality oxygen monitor, also known as an oxygen deficiency monitor, cryochamber personnel can track oxygen levels and detect leaks before a workers’ and users’ health is jeopardized.
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PureAire Monitors

PureAire Monitoring Systems’ oxygen monitors continuously track levels of oxygen and will detect nitrogen leaks before the health of cryochamber operators or users is put at risk. Built with zirconium oxide sensor cells, to ensure longevity, PureAire’s O2 monitors can last, trouble-free, for over 10 years under normal operating conditions.  In the event of a nitrogen gas leak, and a decrease in oxygen to an unsafe level, the monitor will set off an alarm, replete with horns and flashing lights, alerting staff and users to evacuate the area.
Best practice calls for oxygen monitors to be installed anywhere there is a risk of gas leaks. The oxygen monitors should be placed wherever nitrogen is stored and, in all rooms where nitrogen is used.
PureAire oxygen monitors measure oxygen 24/7, with no time-consuming maintenance or calibration required.
Each PureAire O2 monitor has an easy to read screen, which displays current oxygen levels, for at-a-glance readings by cryochamber employees, who derive peace of mind from the monitor’s presence and reliability.

Overview
As dog owners, we treat our pets as we do our children, taking care that the food we give them is not only filling and nutritious but contains only high-quality ingredients sourced and processed in ways that meet our exacting standards.

For many owners, far in the past are the days of grabbing any old bag of kibble off the shelf and feeding it to Fido or Ginger. Dog owners today are making informed choices in their purchases of pet food, such as whether the ingredients are all-natural or organic, whether they contain allergens to be avoided, which proteins predominate in the mix, etc. Not only are owners increasingly educated about what goes into their dogs’ food, they are faced with many choices when it comes to exactly what form the food will take.

Types of Dog Food
Major pet food types available to contemporary dog owners, from a wide array of manufacturers, include dry food, semi-moist, canned, raw, and freeze-dried food.

Dry food, commonly known as kibble, is the most prevalent type of dog food on the market. Semi-moist food is served either on its own or added to kibble for a variety of tastes and textures. Canned food is a moist product with a long shelf life. Raw food appeals to owners who believe that an uncooked all-meat diet is closer to what dogs would have eaten in the wild, before they became domesticated. Raw foods may be produced and sold as either fresh, fresh frozen, or freeze-dried.

Freeze-Dried Dog Food
The freeze-dried dog food segment--including 100% freeze-dried meals, so-called “kibble+” (dry kibble mixed with freeze-dried components), and freeze-dried treats, such as beef liver and other types of training tidbits--currently commands only a niche share of the ~$30 Billion U.S. dog food industry, but it is rapidly growing in popularity among owners seeking, as in their own diets, to avoid highly processed foods.

Purchasing freeze-dried proteins, whether cooked or raw, as well as fruits and vegetables (which are typically freeze-dried in a raw state), allows owners to provide their pets with minimally processed, nutrient-rich, natural foods. Freeze-drying quality ingredients makes for an easily transportable, shelf-stable tasty food that does not require refrigeration.

Gas Usage in Freeze-Dried Food Processing and Packaging
Food safety is as important in the pet food industry as it is in the manufacturing and distribution of human-grade foodstuffs.  Proper temperatures must be maintained in order to prevent mold and bacteria growth resulting from, among other things, improper cooking and cooling temperatures, as well as insufficient or excessive moisture.

Quality control and safety concerns dictate that, because of their rapid cooling and freezing properties, liquid nitrogen (LN2) and liquid carbon dioxide (liquid CO2) be used in pet food production to uniformly cool proteins after cooking, and to freeze them as part of the freeze-drying process. Once properly chilled, the proteins and other ingredients that go into a freeze-dried dog food product are quickly frozen in blast freezers using LN2 or liquid CO2.  After freezing, they are placed into vacuum drying chambers for some 12 hours, until the drying process is complete (i.e., essentially all moisture has been removed), following which the food is ready for packaging.

To prolong dog food shelf life (by inhibiting the growth of mold and bacteria which thrive in oxygenated environments), nitrogen is injected to displace oxygen from the product packaging.The addition of nitrogen during the packaging phase also provides a cushion to protect the contents from settling and breakage that can occur during shipping and handling.

Oxygen Monitors Can Improve Safety in Pet Food Manufacturing and Packaging
While their use is essential in the production of freeze-dried dog food, nitrogen and carbon dioxide can pose health risks (including death by asphyxiation) to employees working in the industry. Nitrogen and carbon dioxide are both odorless and colorless, and they displace oxygen. Absent appropriate monitoring, workers would be unable to detect a leak if one were to occur in a gas cylinder or line. Conversely, by utilizing a top-quality oxygen monitor, safety and production personnel can track oxygen levels and detect leaks before workers’ health is jeopardized.

PureAire Monitors

With PureAire Monitoring Systems’ dual oxygen/carbon dioxide monitor, pet food producers can track levels of oxygen and detect nitrogen or carbon dioxide leaks before workers’ health is at risk. PureAire’s O2/CO2 monitor measures oxygen and carbon dioxide 24/7, with no time-consuming maintenance or calibration required. PureAire’s monitors can handle temperatures as low as -40C, making them ideally suited for environments, such as pet food processing plants, that use liquid nitrogen and carbon dioxide.
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​Built with zirconium oxide sensor cells and non-dispersive infrared sensor (NDIR) cells, to ensure longevity, PureAire’s O2/CO2 monitors can last, trouble-free, for over 10 years under normal operation conditions.

The College of American Pathologists ("CAP")recently imposed new requirementsto address risks related to the use and storage of liquid nitrogen ("LN2") and dry ice.

Background
The new requirements come after a deadly incident in 2017, when liquid nitrogen leaked at a Georgia lab that was not accredited through CAP.  Emergency responders were called to the scene when an employee suffered burns and, moreover,lost consciousness from oxygen deprivation caused by the leak. While the employeeeventuallyrecovered from her injuries, one of the first responders died of asphyxiation as a result ofthe nitrogen leak.
That unfortunate incident illustrates the dangers of nitrogen leaks,which are inherent in the storage and use of LN2. Indeed, there are several cases reported nearly every year of laboratory personnel who die of asphyxiation caused by exposure to nitrogen gas.
Asphyxiation riskis present in dry ice usage as well since, if it is stored in areas without proper ventilation, dry ice can replaceoxygen with carbon dioxide, potentially causing workers to rapidly lose consciousness.

CAP’s New Regulations
Despite their safety risks, both dry ice and LN2 have many beneficial uses in commercial and lab settings, including hospital and research facilities. As such, CAP’s new focus on utilizing best practices to increase employee safety and reduce the danger of nitrogen leaks is vitally important.
Before the regulations were changed, lab directors had greater personal discretion in selectingthe types and deployment of safety equipment utilized in their facilities. Now, laboratories are required to place oxygen("O2") monitors at human height breathing levels anywhere liquid nitrogen is used or stored, and they must place signage warning of safety risk regarding, and train all affected employees on safe handling of, LN2 and dry ice.
Pathologists understand that oxygen/carbon dioxide monitors must be placed appropriately anywheredry ice or LN2 are used or stored.  Even a couple tanks of liquid nitrogen kept in a supply closet pose a safety risk, because even a small leak can quickly displace a large amount of oxygen.
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Oxygen Monitors Protect Laboratory Workers
While many people realize that the use and storage of liquid nitrogen and dry ice can present health risks, they may fail to grasp the speed at which circumstances can become dangerous.  It takes only a few breaths of oxygen-deficient air for one to lose consciousness.

AS CAP recognized, oxygen and carbon dioxide monitors offer an effective solution to the health and safety risks posed by nitrogen leaks and inadequatedry ice storage. O2/CO2 monitors continually monitor the air, and they will remain silent so long as oxygen and carbon dioxideremain within normal levels.However,in the event that oxygen is depleted to an unsafe level (19.5%, as established by OSHA), or carbon dioxide levels rise to an unsafe level, alarms embedded in the monitors will sound, alerting employees to evacuate the area and summon assistance from qualified responders.

PureAireMonitors
PureAire Monitoring Systems’ line of oxygen and dual oxygen/carbon dioxide monitors offerthorough air  monitoring, with no time-consuming maintenance or calibration required., The monitors function well in confined spaces, such as closets, basements, and other cramped quarters.  PureAire’s monitors can handle temperatures as low as -40 C, making them ideally suited for environments, such as laboratories, that utilize liquid nitrogen or dry ice. A screen displays current oxygen levels for at-a-glance reading by employees, who derive peace of mind from the monitor’s presence and reliable performance.
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Built with zirconium oxide sensor cells and non-dispersive infrared sensor (NDIR)cells, to ensure longevity, Pure Aire O2 monitors can last, trouble-free, for over 10 years under normal operating conditions.  That makes PureAire a cost-effective choice forprotecting employees and complying with the new safety regulations affecting labs and hospitals.
Learn more about oxygen monitors and best practices for their use at www.pureairemonitoring.com.